Genital Herpes Sexually Transmitted Disease Essay

Genital Herpes Sexually Transmitted Disease
Genital Herpes is a sexually transmitted infection affecting the genital area of human body. It is a contagious disease caused by herpes simplex virus type 1 or 2 (HSV-1 or HSV-2) of the family Herpesviridae. According to WHO and CDC, genital herpes is more common in United States with 45 million people infected and about 500,000 cases seen every year. Transmission of infection from male to female occurs more easily and is more prevalent in women than men. Pregnant women with infection can pass it on to babies, around 3000-10,000 infected babies are born every year (Marshall Cavendish, 364). One out of six people of 14 – 49 years of age have the infection. Genital Herpes Sexually Transmitted Disease Essay.
Herpes virus is transmitted by individuals who are unaware of their infection and shed the virus by sexual or oral-sexual contact. It is transmitted by the mucous membranes or damaged skin in the genital area or around mouth to the nerve cells where it stays for life (Susan Scott Ricci, Terri Kyle, 154). Some patients show preliminary signs of infection that is severe and painful within 5 – 7 days of HSV exposure during which the virus replicates and later develops lesions that appear as clusters of tiny bumps filled with clear fluid (Sandra Alters, Wendy Schiff, 404). Patients then experience later recurrences that are milder, while some patients have no signs of infection due to the dormant state of virus.
First symptoms of genital herpes are visible sores, lesions and blisters visible in and around vagina, cervix, penis, testicles, mouth etc. causing discomfort and pain followed by fever, muscle pain, headache, painful urination and swollen lymph nodes. Other complications caused by genital herpes are:
Aseptic meningitis is illness due to inflammation of brain linings (Gerd E. Gross, 224). Genital Herpes Sexually Transmitted Disease Essay.

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Recurrent Lymphocytic Meningitis (RLM) characterized by sudden onset of aseptic meningitis recovery and recurrence.
Photophobia
Sacral radiculomyelitis may occur in both men and women due to urinary retention.
Transverse myelitis a neurological syndrome caused by inflammation of spinal cord.
Eye infection
Erythema multiforme a skin disorder caused due to infection or allergic reaction.
Pneumonitis an inflammation of lung tissues etc.
Herpes gladiatorum (epidemic herpes in wrestlers) (Stephen J. McPhee, Maxine A. Papadakis, 114)
The virus hides in the cells of nervous system during the dormant state and is invisible to drugs or the immune system which makes it difficult to cure. Hence there is no cure for genital herpes and the only best treatment is prevention, however, antiviral medications can treat the outbreaks, shedding and recurrence. Oral medications like Acyclovir (Zovirax), Famciclovir (Famvir) or Valacyclovir (Valtrex) prevent the virus replication (Jerrold S. Greenberg, 574). These medications possess certain severe, moderate and mild side effects like diarrhea, nausea, abdominal pain, vomiting, joint pains, high BP, rapid heartbeat, speech problem, fatigue, painful periods, etc (James Balch, 247).
Ways to prevent the genital herpes are:
Having a safe and long term sexual relation with uninfected partner
Use of condoms would reduce the risk as the partner might be asymptomatic. Genital Herpes Sexually Transmitted Disease Essay.
Avoid touching other body parts after touching the sores or blisters.
Regular hand wash during the outbreaks would lead to quicker recovery.
Pregnant infected women should avoid vaginal delivery during outbreak.
Avoid stress and relax more to decrease the recurrence.
References:
1. Susan Scott Ricci, Terri Kyle, “Maternity and pediatric nursing”, 2008, http://books.google.co.in/books?id=gaYtFuND7VIC
2. Stephen J. McPhee, Maxine A. Papadakis,”Current medical diagnosis &amp. treatment 2010″, 2009, http://books.google.co.in/books?id=fG-eYRsiGEkC
3. Marshall Cavendish Corporation, “Sex and Society, Volume 2”,2009, http://books.google.co.in/books?id=YtsxeWE7VD0C
4. Sandra Alters, Wendy Schiff, “Essential Concepts for Healthy Living Update”, 2011, http://books.google.co.in/books?id=EciU_y1JroMC
5. Jerrold S. Greenberg, Clint E. Bruess, Sarah C. Conklin, “Exploring the Dimensions of Human Sexuality”,2010, http://books.google.co.in/books?id=1NC5R0RozBYC
6. James Balch, Mark Stengler, Robin Young-Balch, “Prescription for Drug Alternatives: All-Natural Options for Better Health Without the Side Effects”, 2008, http://books.google.co.in/books?id=w65iAqn_CbsC
7. Gerd E. Gross, Stephen K. Tyring, “Sexually Transmitted Infections and Sexually Transmitted Diseases”, 2011, http://books.google.co.in/books?id=AnoGccgd7yQC
8. World Health Organization, “Sexually Transmitted Diseases”, http://www.who.int/vaccine_research/diseases/soa_std/en/index4.html
9. Wendy Melton, “Side Effects of Herpes Drugs”, December 23, 2009, http://www.livestrong.com/article/67104-side-effects-herpes-drugs/
10. Centers for Disease Control and Prevention (CDC),”Sexually Transmitted Diseases (STDs)”,http://www.cdc.gov/std/herpes/STDFact-Herpes.htm
11. Kallio-Laine K, Seppänen M, Kautiainen H, Lokki M-L, Lappalainen M, Valtonen V, et al . “Recurrent lymphocytic meningitis positive for herpes simplex virus type 2” , July, 2009, &lt. http://wwwnc.cdc.gov/eid/article/15/7/08-0716.htm&gt. 12. MedicineNet.com, “Genital Herpes in Women”, http://www.medicinenet.com/genital_herpes_in_women/article.htm#1whatis
13. Melissa Conrad Stöppler, William C. Shiel Jr, “Genital Herpes”, http://www.emedicinehealth.com/genital_herpes/article_em.htm
14. No Cure for Herpes, http://nocureforherpes.com/
15. Elizabeth Boskey, Ph.D., “Is there a cure for Herpes?”, October 22, 2011, http://std.about.com/od/herpes/f/microrna.htm
16. DermNet NZ, http://dermnetnz.org/viral/herpes-simplex.html

World Health Organization defines health as “the science and art of preventing disease, prolonging life and promoting health through organised efforts of society” (WHO, n.d.). While health impact, can present positive or negative effects to an individual’s well-being or mental health. Sexual activity is known as an essential element of human health and well-being contributing to quality of adult partnerships and a requirement for natural creation and, so the continued existence of humanity. Genital Herpes Sexually Transmitted Disease Essay. Yet it poses a lot of risks to health through transmission of sexually transmitted infections (STIs). Although syphilis, gonorrhoea and chancroid are generally considered as the main STIs, various other pathogens are also transmissible including Herpes Simplex Virus type 2 (HSV-2), Chlamydia trachomatis, Herpes Papilloma Virus (HPV), Hepatitis B Virus (HBV).

The purpose of this paper is to first discuss the public health impact of STIs, followed by the approaches to their control/prevention in the UK. Unfortunately the public health impact of STIs is negative as it causes or contributes to ill-health. In the UK and other parts of the world, STIs pose enormous challenges for the public health which may be individual well-being, mental health or the burden on health costs. Focus of this paper will be mainly on genital Chlamydia, gonorrhoea, syphilis, HIV/AIDS, and Human Papilloma Virus (HPV – [genital warts]) amongst other STIs due to the reported high rates of infection.

Sexually transmitted infections affect people of all ages with the greatest occurrence amongst those under the age of 25 years (Nicoll, 2001; Johnson, 2001; NCSP, 2009). In the UK, certain groups of populations are affected more than others thus creating sexual health (s.h.) inequalities. Primary and secondary syphilis occurs more often in the African community than it does in the White community. Gonorrhoea is reported more commonly among some ethnic minorities while Chlamydia infection rates are disproportionately high in the under 25s. Data on ethnic differences in behaviour and infection susceptibility are meagre and the observed differences are not accounted for. Poverty could be attributable to the high incidence rates in the ethnic minorities as STIs are more common in ethnic minorities than among the white majority which might also be a link between an increased risk and belonging to a minority population. In 2007, women aged 16-24 accounted for 65% of all Chlamydia diagnoses, genital warts were 55%, infections from gonorrhoea were 50% through the genitourinary medicine clinics (GUM) within the UK (HPA, 2008). Chlamydia rate of infectivity at national level for young people aged 15-24 is one in nine supporting the level of sexual activity in that group. Genital Herpes Sexually Transmitted Disease Essay.

The conquest of the majority of communicable disease has been one of the main successes of modern medicine. The diseases have presented the highest causes of mortality and morbidity prior the twentieth century. Until the mid twentieth century in Britain, particularly for women, the pleasures of sex were tempered by the dangers of poor health and social outcomes. However, communicable diseases menace has mostly been contained due to the advancement of contemporary antibiotics and effective vaccines, and remarkably sex became safer.

Although sex became safer, STIs rates significantly increased in recent years in the UK predominantly from unsafe sex practices arising from various factors like sexual risk behaviours and poor infection control. They have become a major public health concern as highlighted in the National Strategy for Sexual Health and HIV (Department of Health, 2001). The 16-24 year age group comprising of only 12% of the population but with the largest diagnosis of STI cases of almost 50% of newly acquired infections. Control of STIs is complicated since many of them are asymptomatic. The economic impact caused by STIs is huge on health services with high costs mostly experienced in the management of infection complications. However, older women and men are also at risk especially those entering into new relationships after breaking up from a long-standing relationship. Hence there is ample requirement for protecting, supporting and restoring s.h. in people.

Public Health Impact of Sexually Transmitted infections in the UK

History

Syphilis and gonorrhoea records have been collected for more than 80 years. In England, Wales and Scotland, diagnosis of syphilis and gonorrhoea was recorded highest in 1946, which coincided with the coming back of the armed forces after World War II (Figure 1). A sharp drop was subsequently detected and was linked to the use of penicillin and the re-establishment of social stability.

Figure 1: Numbers of diagnoses of syphilis (primary, secondary and early latent) by sex, GUM clinics, England, Wales and Scotland*, 1931 – 2003.

*Corresponding Scotland and Ireland data are excluded as they are not complete from 1925 to 2003.

Source: KC60 statutory returns and ISD(D) 5 data.

During the sixties and seventies, there was a stable rise in STIs diagnosis owing to more relaxed mind-sets to sexual behaviour. There was an upsurge in cases of Syphilis in males, while in women the number of cases continued to be stable. This implied sex among men during that time turned out to be the main route of transmission (CDC, 1999).Genital Herpes Sexually Transmitted Disease Essay.  Yet an increase in diagnosis was recorded in both males and females for gonorrhoea, genital warts and genital herpes signifying that these infections were acquired during heterosexual sex. Probably the rise in a small number of the STIs could have resulted from enhanced diagnostic sensitivity or public awareness, adding to higher rates of infectivity.

However, in the early eighties, HIV and AIDS were first reported which supposedly had considerable effect on other serious STIs. A brisk drop of syphilis and gonorrhoea diagnosis was experienced in early to mid- eighties. This happened simultaneously with the widespread AIDS coverage of embracing of safer sex behaviours, and resulted in a subsequent decline in transmission of HIV amongst male homosexuals (Bosch, 1995).

Sexually Transmitted Infections Trends

Since 1998 to mid 2004, cases of Chlamydia infection rose by 108%, gonorrhoea by 87% and infectious syphilis by 486% (Ryan, 2004). Still the young people bear the greatest burden. In 2001, women under 20 years of age had reported cases of 42% from gonorrhoea and 36% of Chlamydia. As reported by the Department of Health (DH), diagnosis of new STIs and other STI diagnosed cases in the UK such as re-infections made in genitourinary medicine clinics (GUM) showed a gradual rise in 1999-2008. The introduction of the National Chlamydia Screening Programme (NCSP) in 2003 and other health screens in England, Wales and Northern Ireland and in 2005 in Scotland resulted in an increase of s.h. screens from 759,770 to 1,219,308. For the same period, there was an increase of HIV tests recorded from 520,278 to 951,148. Genital Herpes Sexually Transmitted Disease Essay. In 2008, uncomplicated infections from Chlamydia, syphilis, genital warts, and genital herpes rose considerably from 1999. Yet for the same year, cases of new diagnosis of gonorrhoea and syphilis were reported to have dropped.

The National Survey of Sexual Attitudes and Lifestyles (NATSSAL) identified sexual behaviour as the risk of acquiring an STI in the young age groups. The factors included lower age at time of having sexual intercourse for the first time, partners frequently changed, increased likelihood of being involved with concurrent partnerships, irregular use of condoms and the increased chances of being involved with a partner who comes from a part the world other than UK that is regarded as high risk (Hughes, 2000; Johnson, 2001, Mueller, 2008; Skinner, 2010). However, the young people appear to be the central part of the risk of passing on the infection to other groups of the population. Thus prevention should be mostly targeted at this core group which would result in economic benefits.

Chlamydia

Chlamydia trachomatis is the most widespread bacterial pathogen transmitted through infected secretions and mucous membranes of urethra, cervix, rectum, conjunctivae and throat following unprotected sexual contact with an infected partner. In addition, an infected mother can infect her baby during vaginal delivery. It is the most commonly diagnosed STI in individuals less than 25 years in the UK (Fenton, et al, 2001; Creighton, et al, 2003). Most people infected with Chlamydia are asymptomatic until a diagnostic test is performed and in most cases they do not seek medical care. Thus, in those individuals affected by the disease, if efficient and effective health measures are not administered, the diases has the potential of causing a significant amount of health complications to women’s well-being including infertility and pelvic inflammatory disease (Golden, et al, 2000; Garnett, 2008).Genital Herpes Sexually Transmitted Disease Essay.  There is also greater risk in those with recurring infection and untreated infections to spread to other reproductive organs resulting in chronic pelvic pains (La Montagne, et al, 2007). The number of diagnosed episodes of Chlamydia infection has been rising over the past 10 years (Figure 1). Furthermore, the economic impact of Chlamydia infections on the health service is enormous with high cost in the management of female health complications arising from Chlamydia infection (Garside, 2001; Simms, 2006). Because of the impact of Chlamydia infection on the health of young people, it is important to identify and treat infected patients and their partners and as a result reduce the burden of the disease on the people and health systems.

Figure 1: Rates of genital Chlamydia infection by sex and age group (1995 – 2004).

Source: Health Protection Agency, London

In men Chlamydia infection causes epididymo-orchitis and urethritis. Also rectal pain, discharge and bleeding occur from proctitis which is from infection of the rectal mucosa. Additionally, individuals can develop dysuria after their treatment for gonorrhoea causing postgonococcal urethritis. Genital Herpes Sexually Transmitted Disease Essay.

HIV/AIDS

In nearly three decades, ever since HIV was first identified, HIV infection has turned out to be a deadly disease and has caused a disturbing adversity to humans, in almost all areas of life. In the early eighties, when the first few cases of AIDS were reported, few might have realised its propensity to become a global public health problem. The UK is facing a s.h. crisis. Between 1999 and 2002, HIV prevalence rose by about 20% annually, and almost a third of HIV-positive individuals did not know their HIV status (Fenton, 2002). Furthermore, the increase in rates of HIV infections could be brought about by the rise in STI incidences in the public as already highlighted in this paper. In 2004, a minimum of 49,000 individuals had HIV in England.

The disturbing extent of its increase, infection, very long incubation phase, secondary susceptibility of spread and the absence of a vaccine to prevent it calls for attainment of comprehensive information about the disease. Currently, AIDS prevention mainly relies on health education and behavioural modifications based on AIDS awareness, predominantly in the high risk group of young people.

Gonorrhoea

Gonorrhoea infection is caused by an organism, Neisseria gonorrhoeae (N. gonorrhoeae) which is highly infectious and a bacterial sexually transmitted pathogen. In heterosexuals, its occurrence is associated with age (<25 years), black ethnicity, and socioeconomic deprivation. It is estimated that the disease may possibly be more common in men who have sex with men than in heterosexual men (McMillan, 2000; Bignell, 2006; HPA, 2008). At the endocervix and urethra in women, the disease is also asymptomatic, and usually (>90%) asymptomatic in the rectum and oropharynx in both women and men (Hook, 1999; Knox, 2002). In the GUM clinics and various health services, testing for N. gonorrhoeae is a core factor of screening for STIs.  Genital Herpes Sexually Transmitted Disease Essay.Although there is not much evidence to direct testing, every mucosal site correlated with the disease symptoms ought to be tested for infection (Barlow, 1978; Harry, 1997; CDC, 2002; Ghanem, 2004; Bergen, 2006). Screening measures are subjective to an individual’s sexual history and repeat screening may be encouraged (Miller, 2003). The number of new gonorrhoea infections in the United Kingdom dropped from 18,649 in 2007 to 16,629 in 2008, the lowest number recorded since 1999. Its treatment is simple through the administration of antibiotics orally or as an injection but recently some strains have resistant (Frenton, 2003).

Syphilis

Syphilis is caused by infection from Teponema pallidum subspecies pallidum, is a mucocutaneous STI with high infectivity in the early infectious stages. It may also be transmitted through the placenta in pregnant women from week nine of gestation onwards. Screening is recommended for all asymptomatic patients attending GUM clinic or those attending other health services are referred appropriately (Nicoll, 2002). Incidence of syphilis also showed a 4% fall, from 2,633 in 2007 to 2,524 in 2008, (HPA, 2008). Over the last year, there has been almost three times the number of heterosexual cases of syphilis in south London than were diagnosed in 2001 (25 in 2001, 72 in 2002 and over 40 cases in the first five months of this year) (Fenton, 2001; Poulton, 2001; HPA, 2008). Infection from syphilis is controllable and treated with penicillin as the best recommended or doxycycline as an oral substitute. Genital Herpes Sexually Transmitted Disease Essay.

Human Papilloma Virus

The spread of genital HPV is normally spread during intimate, skin to skin or sexual contact. It is also asymptomatic and can be dormant for years. HPV high risk strains are 16, 18, 31, 33 and 45, which are likely to increase the probability of getting cervical cancer. These strains exist in nearly every woman with cancer of the cervix. Although HPV testing is still not regularly accessible, the National Health Service is considering it to be included in the screening programme of cancer of the cervix. Women who test positive for high risk types of HPV are more likely to need treatment for borderline or mildly abnormal cervical smears. Although in ninety percent of HPV cases, clearance of the virus occurs naturally within two years. Yet, continued use of condoms may possibly facilitate in lowering the risk of infection from genital HPV. Infection from HVP is now being prevented through administration of vaccines for types of HPV that causes cervical cancer (Wallin, 2002; Winer, 2006). In 2007, the UK DH licensed Cervarix as a vaccine against cervical neoplasia for use in 12-13 year old girls.

However, the genital warts strains 6 and 11 normally develop within weeks or months following sexual contact with an infected partner who might be asymptomatic. Sometimes if treatment is not administered, they might disappear, or remain unaltered and not cancerous. In 2007, genital warts were the most commonly diagnosed STI accounting for 49,250 cases showing an increase of 8% from that in 2006 (HPA, 2008). Genital Herpes Sexually Transmitted Disease Essay.

Approaches to prevention and Control of sexually transmitted infections

The health of the people and the social and economic success of the UK are extremely connected. The related economic and social costs to public health are enormous and surpass UK’s future. Marmot’s (2010) six recommendations further support the prevention and control of STIs in UK’s population. In two of the six recommendations he states that, “enabling all children, young people and adults to maximise their capabilities and have control over their lives” and that of “strengthening the role and impact of ill-health excellent well-being over their lives”. It is vital that UK’s population is educated on s.h. issues so that they are able to make well informed sex decisions that contribute to their well-being and reducing the burden caused by STIs. Marmot’s report further emphasised other research work (Picket & Wilkinson, 2009) that “it is not only the poor who suffer from the effects of inequality, but the majority of the population”. High priority should therefore be given to the integration of STI control measures into primary health care. The worldwide interest in and resources committed to preventing AIDS provide a unique opportunity for health workers to make considerable progress in controlling the other STIs.

Control programmes for STIs will continue to be the most prominent in public health management and have been at an increase since the mid nineties with rates of unwanted pregnancies still being reported high. Strategies to prevent transmission of organisms spread by intimate human contact must remain flexible and adapt to the social, technical, clinical, financial and political realities. Genital Herpes Sexually Transmitted Disease Essay. A strategy of primary prevention, based on sexual behavioural change combined with the provision of adequate clinical services, is vital for the control of STI. In response to the re-emergence of these diseases in the UK, it was decided by the Department of Health to open for the first time ever STI clinics (GUM) across the country to help reduce the burden of the STIs. These clinics are staffed with a multidisciplinary group of specialists that offer s.h. services to different age groups of the community.

Given the unequal burden of STIs for young people, it is imperative to ascertain effective prevention programmes. Although enhancing access to Chlamydia testing has been an important and urgent focus of the NCSP and has led to renewed efforts to increase access to Chlamydia testing (WHO, 2001; Santer 2000; Santer, 2003). While more people learn their Chlamydia infection status, factors related to Chlamydia awareness remain crucial to identify in order to design comprehensive Chlamydia management services that meet the needs of the population at risk of infection (Brabin, et al, 2009).

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Responsibility for the National Chlamydia Screening Programme (NCSP) was taken over in 2005 by the Health Protection Agency from the Department of Health. Screening is conducted in various locations across the UK, the main ones being youth services, community contraceptive services, general practices, education premises (universities or colleges). This oversees all the screening plus s.h. awareness media campaigns. More partnership work is required to tackle the variances including that of offering screening in health clubs such as gyms and boxing clubs. Genital Herpes Sexually Transmitted Disease Essay.

Presently prevention and control of STIs is aimed at minimising the period of infection (i.e. early diagnosis and treatment), reducing the number of susceptible persons and reducing infection transmission (modification of sexual behaviour plus frequent use of condoms). A study by Shiely, et al (2009) showed that in Ireland, age specific behavioural interventions could be effective by targeting increased use of condoms to decrease STI incidences. Also in order to boost condom use, a 5% reduction from 13.5% in taxation on condoms could be implemented at policy level. Other studies also revealed age as a risk factor for STI transmission and to that regard there should be enhanced sex education promotion to the target group to enhance behavioural changes ((Holmes, 2004; Manhart, et al, 2004; Fenton, et al, 2005). A further study also showed that diagnosis of a viral STI was not associated with multiple partners but however it was possible for females who had more than one sexual partner to be more likely to use protection since they will be more experienced and aware of STI infection (Fenton, et al, 2005).

Although there has been a rise in frequent use of condoms universally, in the UK the scale of their usage is still low. The enormous differences could be associated with economic and social causes of sexual behaviour which further affect intervention. While personal behaviour modification is fundamental to s.h. enhancement, attempts should be made to tackle those that relate to the social circumstances thus addressing factors that play a part to risky sexual behaviour (Wellings, 2006). More work is required to tackle the menace from STIs by the provision of comprehensive s.h. education, promotion of s.h. interventions, easy access to s.h. services, high quality individualised s.h. education to empower those at risk.

Accomplishing excellent s.h. for the population of the UK has always created its own distinctive challenges. Meagre s.h. is often disproportionately impacting on those who are already at risk and experiencing inequalities, for instance the young people, black and minority ethnic groups, those in lower socio-economic class, and gay men. Thus the need for comprehensive behavioural interventions that would tackle the social context for individual-level programmes, support and sustainability of behavioural change, and the structural factors that is contributory to risky sexual behaviour. Genital Herpes Sexually Transmitted Disease Essay. STIs have been shown to be important cofactors in HIV transmission (Fleming, 1999). New approaches to STI control and prevention are needed to reduce the spread of infection and minimize associated suffering.

The National Institute for Health and Clinical Excellence (NICE) suggested the need for health professionals to identify individuals at higher risk of becoming infected with STIs, ascertained by one’s sexual history, and organize one to one talks to minimise the risk of infection. However, the s.h. guidance recommends a variety of circumstances for assessing risk of infections which include opportunities where a patient seeks contraception, abortion or pregnancy or when conducting cervical smear test, obtaining STI test, obtaining travel immunisation, and during regular care. Additionally for those who have been tested positive, should be assisted in having their partners tested and treated. Genital Herpes Sexually Transmitted Disease Essay.