Advanced Pharmacology Essay Discussion

Write a 2- to 3+ page paper that addresses the following:
· Explain how the factor (i.e. genetics, gender, ethnicity, age or behavior) you selected might influence the pharmacokinetic and pharmacodynamic processes in the patient from the case study you were assigned.
· Describe how changes in the processes might impact the patient recommended drug therapy. Be specific and provide examples.
· Explain how you might improve the patient drug therapy plan and explain why you would make these recommended improvements. Advanced Pharmacology  Would you discontinue any medications, change the dosage, and/or add medications to the patient regimen? DISCUSS EACH MEDICATION.

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Case study assigned

LM is an 89-year-old female resident of a long-term care facility who has been experiencing multiple falls, some resulting in injuries such as bruising and skin tears. Over the last 6 months, her ambulation status has declined from independent to wheelchair level. She complains of pain in her legs when walking more than short distances across the nursing unit.

PMH:

HTN
Alzheimer’s disease
Hypothyroidism
Osteoarthritis
Diabetes

MEDICATIONS:

Amlodipine 10 mg QD
Donepezil 10 mg QHS
Levothyroxine 88 mcg QAM
Celecoxib 200 mg QD
Furosemide 40 mg QAM
Metformin 500mg, 1 BID
Glyburide 5mg, 1 BID

ALLERGIES: NKA

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SOCIAL HISTORY:

Widowed with 2 adult children living in town, retired photographer and owner of an art supply store

HEENT: Normocephalic, no evidence of trauma, PERRLA, EOMI
CV: RRR
Respiratory: Clear to auscultation bilaterally
Abdomen: Soft, non-tender, no masses or guarding
G/U: Skin intact, assisted with toileting and personal hygiene by staff
Extremities: Bilateral 2+ edema to lower extremities; skin dry, dark bruising and skin tear to right elbow and forearm
Neuro: Alert and oriented to person only. MMSE 18/30, stable over last 12 months

PAIN ASSESSMENT:

Faces pain scale: No pain occurs at rest, upon walking, pain is moderate to severe

Advanced Pharmacology Essay Discussion